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Arthritis and Joint Deterioration

Date: 9th December 2008, Source: Althealth News

Every day our joints endure an enormous amount of stress from physical activity, including walking, lifting, and typing. Despite this heavy and constant use, we take our joints for granted and expect them to function trouble-free for several decades.

If you’re a baby boomer, like I am, and for so many years took for granted pain free joints. We find ourselves now looking for a solution to this problem. I’ve done some extensive study on the solution and believe this information could be helpful.

Cartilage
Cartilage is the protective layer that cushions and lubricates the joints. Over the years, the cartilage in our joints is gradually worn down due to normal physical activity. The body rebuilds the cartilage as it is worn and replaces shock-absorbing synovial fluid, so the joints are always protected. For various reasons, however, the production of new cartilage and synovial fluid can fall behind demand. Because of poor blood supply, lesions to articular cartilage do not heal at the same rate as other tissue in the body; cartilage is rebuilt slowly, and if components of the substances used for cartilage repair are in short supply, the recovery from damage can be slowed even more.

Glucosamine
Glucosamine, an amino sugar, is an important precursor in the biosynthesis of cartilage. Specifically, it is a building block of proteoglycan-protein molecules with a high content of bound carbohydrate. Proteoglycans and collagen compose the majority of the cartilage matrix. Proteoglycans are essential for healthy cartilage, because they bind the water that lubricates and cushions pain and osteoarthritis may result.

In addition to its role as a biochemical precursor, glucosamine is believed to play a role in regulation cartilage formation and normalizing cartilage metabolism by encouraging higher production of collagen and proteoglycans. Glucosamine also stimulates synovial production of hyaluronic acid, which is responsible for the lubricating and shock-absorbing properties of synovial fluid

Numerous double-blind clinical studies have shown the efficacy of glucosamine supplements in maintaining healthy cartilage, healthy joints, and a full range of motion in the short term. More recently, a three year study was published showing that joint space increased in the glucosamine treated group, while it continued to decrease in the placebo group. Indicating that the protective cartilage was better maintained in those who used glucosamine. Additional studies have demonstrated that glucosamine, taken orally, is well absorbed and diffuses into tissues, including the articular cartilage.

Blended Products Proven To Be Powerful
The combination of glucosamine sulfate with turmeric extract, manganese, vitamin C, and silicon represents a more comprehensive approach to joint health. Over the long term, these ingredients help retain healthy cartilage. Gluconsmine sulfate promotes the incorporation of sulfur, a component of protein, into the cartilage matrix. Turmeric contains curcumin and related compounds known as curcuminoids, which have good antioxidant properties. Manganese is required for enzymes involved in the biosynthesis of proteoglycans. Vitamin C is essential for the reactions necessary to collagen formation. Silicon is required for proper collagen formation and ultimately cartilage composition.

   
   
 
 
 
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